Wednesday, 21st May AUS-oMicS 2025

Thermo Breakfast Workshop - From Core Facilities to Cutting-Edge Discoveries: The Evolving Landscape of Proteomics and Metabolomics
Presenters:

• Ralf Schittenhelm, Director of Monash Proteomics & Metabolomics Platform: Showcasing Research Enabled by the Monash Proteomics & Metabolomics Platform
• Laura Dagley, Proteomics Facility Manager , WEHI: Advancing Proteomics for Biomedical Discovery with the Orbitrap Astral Mass Spectrometer: Tales from a Core Facility

• Identifying the Regulatory Network of the O-GlcNAc-transferase in the Ischemic Heart - Natasha E Zachara

• Mapping the Influenza Immunopeptidome: defining conserved targets for Influenza immunity - Patricia Illing

• Visualisation of therapeutics at the subcellular level with elemental and isotopic imaging - Haibo Jiang

• Mass Spectrometry-Driven Discovery of Weak E3 Ligase–Degron Interactions Across the Proteome for Targeted Protein Degradation - William Alexander Donald

• MultiScholaR: Enabling Reproducible Analyses and Integration of Multi-Omics Datasets Through Easy-to-Follow Scripting Templates - William Klare
• An Inter-laboratory Study on Single-Cell Scale Label-Free Quantitation for High Accuracy and Precision with the Orbitrap Astral Mass Spectrometer  - Daniel Hermanson
• A True Mix-and-Measure High-Throughput Screening Approach Using Collision-Induced Affinity Selection Mass Spectrometry for Rapid Ligand Discovery - Xinru Xue
• Analytical Methods for In-depth Characterisation of Cell Culture Bioreactors: A case study - Janik Seidel
• Analysing non-proteinaceous ubiquitination via NoPro-clipping - Marco Jochem

• Developing native mass spectrometry as a screening method for RNA-targeting small molecules - Louise Sternicki
• Glioblastoma: development of better chemotherapeutic treatment - David G Harman
• Enhancing Eicosanoid Stability for LC-MS Analysis Post-SPE: Investigating the Role of Ethylene Glycol - Jaya Ajay Singh
• Modified trypsin digestion protocol to improve protein sequence coverage and minimize artifactual modifications in bottom-up proteomics - Breyer Woodland
• Native mass spectrometry studies toward a robust analytical framework for DNA triplexes - Gerardo Urbina

• MAD.VB (MA Data Visualisation Dashboard): a software tool for quickly extracting key insights from metabolomics and lipidomics data via interactive visualisation - XIAOCHUAN (Harry) WANG
• MA.NIAC – an accessible Stable Isotope Tracer Metabolomics pipeline - Andrew Isaac
• Multiomics-driven discovery of a novel oxidative pathway for pinoresinol degradation in bacteria - Gunjan Pandey
• Metabolic Disruption Caused by Dimethyl Sulfoxide (DMSO) and Perfluorodecanoic Acid (PFDA) Toxicity in RTgill-W1 Fish Cell Line - Thomas Nguyen
• Reproducible application and comparison of multi-omics integration tools with the moiraine package - Olivia Angelin-Bonnet

• A comparison of Neu5Gc glycans between healthy humans under differential diet conditions. - Nicholas J DeBono
• Protein de-N-glycosylation uncovers differential expression of CD36 glycoprotein in human adipogenesis - Katherine Wongtrakul-Kish
• GlyComboCLI: A Command Line Interface for High-Throughput Glycan Identification in Mass Spectrometry Data with Integration into Major Analysis Platforms - Maia I Kelly
• Thermal glycoproteome profiling for high-throughput discovery of functional N-glycosylation sites - Shulei Liu
• Small extracellular vesicles isolated from breast cancer patient plasma exhibit unique glycomic and proteomic signatures - Shriya Agarwal

• Lipidomics in Action: Bridging Fundamental Research with Translational Applications - Coral Barbas